The guys from www.prezi.com have made a wonderful new way of creating slideshows. The whole nature of a slideshow is changed to a trip over a map, following a path.
The freedom in throwing away the "slide" part of shows is simply brilliant. Mindmaps, cooperative creation, news ways of integrating pictures... This is a paradigm shift in presentation. I heard the guys at TED invested some money in this. Check it out!